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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd4a3b68a140be632cb442a3e354da94c19ed92ff6375e4f92d258109c8dd1a80' 
  AND token = 'fn4Ze4rhpNmBUORB9Azrnawr2iAz7FzmUMgZVbj9QQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}