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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3755d711f71b1f44229321a0acfecf9b040742b985d82bc762e8a35c15bf023a' 
  AND token = 'v6znW5OARm+O0DFoXegloE7aynD1fev/T2aJMzSzsgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}