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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22c1ccd1a3e7c8c570125c8b9e9faa59aebe9f12c31417594b9a673b986755ec' 
  AND token = 'OwS7tLKl03hYvhGQvZnGmAIP1dHgMsB3aPtr1LM36h0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}