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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2cde4165157bb989e0d93c1e710d29729c6aa2a210bd76d501f9e3020a463bfe' 
  AND token = '6Du6lObKUcWq+DzZcdH0xVAmfpG3FeuIjjFk+N6xqYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}