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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '17f42b114ca70f7440ecca07ddaca350fff3b864b626819f413ee7317db06b15' 
  AND token = 'sOSgHRBQJRRooMtFgHLA9IoumN+uLboYMzEMyf6G/sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}