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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65dc7600e43509c1116649d753538682fe3ed98b9a71b69c98043c850b2f8722' 
  AND token = 'j2hmlDC3TA2OfxjO6OpNrTawJjH3lSl3fD8JYG7HNJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}