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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f9293c9623ee2cf51a2cfca9ee470ea7407b2b1d74b29890c64626e5a4501c65' 
  AND token = 'MiMPO9nd57sDGoxdvaXOqHW/6lvHhmCQbQ/qhqVeJe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}