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SELECT 
  1 
FROM 
  cscart_aprilec_print_temp_designs 
WHERE 
  session_id = 'N0JG-Q2GC-FFLS-9ST9-K3DB-1KF5-III4-FTER' 
  AND product_id = 118 
  AND expires_at > 1777988652 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}