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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f78e7d8c530bb9c47943829ea98fe88ab58cb48bed598fffc4f4ee06948956d3' 
  AND token = 'vnoh7k5dPLTyXI1qps3CUklVNcTauxwq1uMVkgwpXZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}