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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f378ecec12dcc726c67cea77abfe6cfe91425e7e10eaa2491e6c9d1225a2ea05' 
  AND token = 'TF11URgx6yDo05qqdUEKJYUoMyL5iK3cXcZhCH7s7mI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}