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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '675b4bd3efddf544b27121a050e490e98b6ff487c28f04197468afdd9318e298' 
  AND token = 'Vyuxg4l0KN0MEZ4FToSnbha2YXv4s2uTixBGyk394gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}