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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6248e19df1e3aba2414efe835de1d8e51aeb54a7fc238f365bbd33900fe6ef8c' 
  AND token = 'LdSzZVC4i+gVaFsbstK1kQghyrl5r0E4z2ATtTPplkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}