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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5a1429f4ac991aed8f76a9179a27fb418eeda388df5e5e9567b65e867d2c3e3' 
  AND token = 'HQRdj0W6nW8Pqx5XT+dOz6LVj6JjbpXQ0zCoiM3QVAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}