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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4d2d31514b658e1a342c62e08fd1a68cabdb038f6247344e976c63381c6e7637' 
  AND token = 'PehuYwlQc6JYPYrcpntyJ916Ka6xtNnKAC6hqbN1GUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}