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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7cfd9cd96bbd2305776dc6e74f36a2f482acfaa76152d72f666b71b0d2d938dd' 
  AND token = 'VPuJgFq1gviMsdAob6VrhTy7nzYanXEH6KWRoW5/t5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}