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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '99c8d34c848deef85a58dbbfa3156dcb950a8f82e9f0439fc7344468d2e618a5' 
  AND token = 'mFkIIV9EBYaQKDWbrRGwbE9fMDYDcxewd1B/vuXlGx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}