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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5b2bcff8ae79acc47ca2ffa449bf214cc124ba7b1b90583a779b8f1992815db' 
  AND token = '0sFrCej8MG8YZHfBJJMJGK/FPsLXEg2kMXGpAcY8Dw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}