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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e192868186f21d5abdea2d92846d0e021b83ead9b2f0497e794ade5995990578' 
  AND token = 'cileKK2540zuDNnfJZQQZ9eBybhc4YkG3FWvj15g42E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}