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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '28a0543c07a9fb36168b282152e839ccf800360ab3cdbdf1d5ce28c27ece8bb4' 
  AND token = 'PLiqUULoWXUfEVFI/TSiYW2K257UhndWeqvDst/O16E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}