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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '143df9cde03c375a6125b1b3ffb7bad499345f56072e53337e36400df55bea64' 
  AND token = 'zN9AXtw6mNwhsV69EEZp1R/ESkp5CQQVgfxLpa5Rlwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}