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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0b251f54f44f5ad3b6dc709b932cf2b8a269aae18ca542a92ad820e020343b6a' 
  AND token = 'jrs8pCY67IYbG1GLZ6+pCs9kNmZKRYICuA9cxvpL/b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}