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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b265654e1d5280905f9c8f42ad53a83c332f508e2595ec58c597cc966add2c2' 
  AND token = 'RPBnNAeTXGXZsVqRlDH496CwU2WVA8aac8ft5kJOswk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}