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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8d21158841b65d99dc25fbf61be81f2d2c4d2c955a2151ce8631e642efc6d5a5' 
  AND token = '3Z4SwSuygfKnp3bLqp+1GUnkUFMbCkXFP8tkysi/OuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}