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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '03e591750b35f9648ce1232d5206c8479bb5876b85c44b8eb15fe3b1128e71dc' 
  AND token = 'w/X6QWsJSfOELnfNfpfO5SK/MrPsNKCQEZmFPsKn2Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}