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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '11da7eaae7b2e8af98f1dd8103017a591dda7fd0c88a1a27bf75fb1622251147' 
  AND token = 'MyqFMFFxRQlAFYAYKCqWI1AceHpipVK2HlZSjJazXPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}