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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cd64d7abfb882e29b023878e2d27d05a61c99eac0519dd0ee7bd602551b419a2' 
  AND token = 'zdUT+1NG08nykAJ+Ee3FAWFWcmEIQnCdO79Mwn9XiV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}