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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '09d40147072b808d53e47999a38a52c72eca86a9564da3df3c536e9fdf46c5f6' 
  AND token = 'sRgTuEzDh2Y54q23oh8rwi1MVEI8kCxawlQxD1gVtSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}