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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5cebb0c2da15a06dbdf4f572c4289516f1e5b980732ecba6002a6c486f1ba48d' 
  AND token = 'tHBzbEt0YQZICAxoE3vu3ei1VESXlqmstJTusByPHEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}