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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cc221916ec5d48a705686641c366450a163dcf6aa4076da336d5bca08cdeeead' 
  AND token = 'dVQ0NadWZPeEm72I8HBT0owZWvYkL5M8CcGC0s+5xXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}