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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6d1bce6322edfde5842516362762eed22288d35e50b41a166d19f3406b9fe321' 
  AND token = 'HyT9ZSClaxY3bdxR26wl7kTjVtb0WYvbbyQLXMLEqTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}