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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25c54f6d79654bb189b1dca2e8dc34ececfc17229c69986a2eca05a5c5a92807' 
  AND token = 'OMWwYlqhQNpRFdYdflbmJpSjOA3vqH9O426cvlVbTc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}