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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45dd13f1481dd9326dd0bf5a44976e8e162bf2a8aadb74a770bb31dffa45de5c' 
  AND token = 'gdF2W/VzdneN/Ums1zD2TIAyTVZjU+7lLNwWyEeu9g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}