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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ab7e778e5431eaad388cd1adf31dcd57f427102f115e54a0e65c305705259ef7' 
  AND token = 'GQRMxUdiZJ3R3BjrXK421C6GPQeKN0euTL5R6OqXB6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}