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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '539b0e42906a477a4800a1091cd4e139465c3a6d72f65e1be49f7bf02790203c' 
  AND token = 'RadThDkAox6heRw3j2jd0tGs2CBF7sMOi7vPBiA9xPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}