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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd4066ee00908f4dfd56ae8b24d3f82661860990055b5cb7811be8de6e5910320' 
  AND token = 'oZAfGl5OjF2xVeNzK85d64/EfayaGGgTHGF7VdPkSF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}