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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a709ec52d05c2423c1ae5ba4be7acb1526528a65e345fa9c9a40b395fc2d7122' 
  AND token = 'JlFv0pz2HzTCNRwX6iJhr2rPKGaJbg/hlF+1RRsRhJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}