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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '262ee52afce3faec71a32264966ea7e5810aac6029c7e4398966de15e1e8e9bf' 
  AND token = 'ryC+8dT448qaqyYE08/wW2JfI/+Y0nFCwzHWt44/I44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}