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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '40f05861e5f47a4e18d864d6f16241fe9f011496d8f9ef0749115cc9d36b5e57' 
  AND token = '385IN0yEUYzR/ouno80eikIzXdWPeYdXJOLT/wI1iaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}