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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f226c6caed75bb0c7396bb7c6b8645535ee9f1d7f699b0ffc951e6895a19268e' 
  AND token = '/RCJEoGHRltM/RVTDEhPQ5/4mP6+SkJYOMoAk6Ir90s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}