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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3368f33a5f3c3527c8220691a08acba84121eed3577abc1a2214e0c637dee503' 
  AND token = 'aNSR+VbgzRgdHzExr+LlslOzu88/+qpWsar3gneP2+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}