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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4909914d50ae1921e3b69871d7b4262eda16c25418f032555087b701dad50d61' 
  AND token = 'ydtXnPUfy+OWvELc1CHJ1R6sHKny6DKkKHVJarmaxc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}