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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '100958b9d9cdaadd149821b3f1f49f78e046344409a17cc90156d86b92223448' 
  AND token = 'G64tYxsMAkDetOLdr+0EtG5i3h8WBxHFW344RLtVOjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}