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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '16db5e95037de36887987d7706f122876df741c3b9fabf820e048e687b4df520' 
  AND token = 'Dd0tdkF9KEHxTArzaKjyj3b+tohhBabYHtS9Tgq4vcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}