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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cf24c3bec2205b65ee21beadece7150ac18848a31bb71dee97d8cb4050eba479' 
  AND token = 'KRiBruAQmHWYGJqi1TDeOXDDrD2pPj/VRdWzEcDsW1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}