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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6283b487f78d17f2e46eec69f18646cef0f270859067e40446137443dbf82891' 
  AND token = 'D6E8UQ51S0Qi4VwwIyPIZam2HoYEiRS2W9TV9OT/OEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}