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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fdbc2f1bf40fb786e00300989e1b2d2f543256ffb8e5123eb3925277f175caa2' 
  AND token = 'V7AJyysBb/UUE8rOpubLwqiPh33RgVtujD10bRmflSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}