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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b8d1280be8cb59a5f789ab17ed155fa6bb89ca1043cf8b5f05f6b5daab30e921' 
  AND token = 'O+FLInLfstHUnXl7L8XL0jgNRgEldZhMNDLGtgRS2jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}