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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '790d0047b7de53363d737516ebaed1a60b8e0726259843a4dcc456a64b3ad154' 
  AND token = 'HKsC50EfCYXkYJzCES0KWRx42gZiM5ddU9P+arXuLHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}