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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21b33616a3fa0f779aa2545985968a708c103a229687dfacf731bb46fb5052ff' 
  AND token = 'fte9pyPCN9Pd3Xi7Pj5zCFJJT0fPG2E52aScoKjOwvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}