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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '35cf4b82c11e752f4222e5776e668251d72271bca3b705901ae18d430fd709da' 
  AND token = 'JrIVcxk/W/ERXdJcyCedj40tNMedfsKR8MpwTbuWiVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}